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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA015950LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA015950LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA015950LA01HU at dilution of 1:100

NOTCH2 Antibody

CSB-PA015950LA01HU
Cusabio
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetNOTCH2
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Overview

  • Supplier
    Cusabio
  • Product Name
    NOTCH2 Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4853
  • Target name
    NOTCH2
  • Target description
    notch receptor 2
  • Target synonyms
    AGS2; HJCYS; hN2; neurogenic locus notch homolog protein 2; notch 2; Notch homolog 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ04721
  • Protein Name
    Neurogenic locus notch homolog protein 2
  • Scientific Description
    Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells (PubMed:25985737).
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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