IHC-P analysis of mouse lung tissue using GTX03453 NOTCH4 antibody. Antigen retrieval : Heat mediated antigen retrieval step in citrate buffer was performed. Dilution : 1:100

NOTCH4 antibody

GTX03453

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

TargetNOTCH4

Overview

Supplier
GeneTex
Product Name
NOTCH4 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:2000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID4855
Target name
NOTCH4
Target description
notch receptor 4
Target synonyms
INT3; neurogenic locus notch homolog protein 4; notch 4; Notch homolog 4
Host
Rabbit
Isotype
IgG
Protein IDQ99466
Protein Name
Neurogenic locus notch homolog protein 4
Scientific Description
This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203