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ProductsBack/NOX4 Antibody, FITC conjugated

NOX4 Antibody, FITC conjugated

CSB-PA015961LC01HU
Cusabio
ReactivityHuman
Product group Antibodies
TargetNOX4
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Overview

  • Supplier
    Cusabio
  • Product Name
    NOX4 Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID50507
  • Target name
    NOX4
  • Target description
    NADPH oxidase 4
  • Target synonyms
    kidney oxidase-1; kidney superoxide-producing NADPH oxidase; KOX; KOX-1; NADPH oxidase 4; renal NAD(P)H-oxidase; RENOX
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NPH5
  • Protein Name
    NADPH oxidase 4
  • Scientific Description
    Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203