
IHC-P analysis of human spleen tissue using GTX31588 NOX4 antibody. Working concentration : 5 microg/ml
NOX4 antibody
GTX31588
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNOX4
Overview
- SupplierGeneTex
- Product NameNOX4 antibody
- Delivery Days Customer9
- Antibody SpecificityAt least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins.
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID50507
- Target nameNOX4
- Target descriptionNADPH oxidase 4
- Target synonymskidney oxidase-1; kidney superoxide-producing NADPH oxidase; KOX; KOX-1; NADPH oxidase 4; renal NAD(P)H-oxidase; RENOX
- HostRabbit
- IsotypeIgG
- Protein IDQ9NPH5
- Protein NameNADPH oxidase 4
- Scientific DescriptionThis gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ursolic acid reverses liver fibrosis by inhibiting NOX4/NLRP3 inflammasome pathways and bacterial dysbiosis. Nie Y et al., 2021 Jan-Dec, Gut MicrobesRead more