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IHC-P analysis of human spleen tissue using GTX31588 NOX4 antibody. Working concentration : 5 microg/ml
IHC-P analysis of human spleen tissue using GTX31588 NOX4 antibody. Working concentration : 5 microg/ml
IHC-P analysis of human spleen tissue using GTX31588 NOX4 antibody. Working concentration : 5 microg/ml

NOX4 antibody

GTX31588
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNOX4
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Overview

  • Supplier
    GeneTex
  • Product Name
    NOX4 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    At least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins.
  • Application Supplier Note
    WB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID50507
  • Target name
    NOX4
  • Target description
    NADPH oxidase 4
  • Target synonyms
    kidney oxidase-1; kidney superoxide-producing NADPH oxidase; KOX; KOX-1; NADPH oxidase 4; renal NAD(P)H-oxidase; RENOX
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NPH5
  • Protein Name
    NADPH oxidase 4
  • Scientific Description
    This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ursolic acid reverses liver fibrosis by inhibiting NOX4/NLRP3 inflammasome pathways and bacterial dysbiosis. Nie Y et al., 2021 Jan-Dec, Gut Microbes
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