NSC 617145

AbMole BioScience

NSC 617145

9

203115-63-3

Research Use Only

C13H10Cl4N2O4

400.04

NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor,IC50 The value is 230 nM. NSC 617145 inhibit WRN ATPase and induce double-strand rupture (DSB) and chromosomal abnormalities. NSC 617145 is selective to WRN and superior to BLM, FANCJ, ChlR1, RecQ, and UvrD helicases.

12352200