NSC697923

MedChem Express

NSC697923 [343351-67-7]

10

343351-67-7

Research Use Only

99.93

C11H9NO5S

267.26

NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-kappaB signaling. Antitumor activity [1] [2] .

O=S(C1=CC=C([N+]([O-])=O)O1)(C2=CC=C(C)C=C2)=O

-20°C,2°C to 8°C

12352200