NSC697923 [343351-67-7]
HY-13811
Overview
- SupplierMedChem Express
- Product NameNSC697923 [343351-67-7]
- Delivery Days Customer10
- CAS Number343351-67-7
- CertificationResearch Use Only
- Estimated Purity99.93
- Molecular FormulaC11H9NO5S
- Molecular Weight267.26
- Scientific DescriptionNSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-kappaB signaling. Antitumor activity[1][2].
- SMILESO=S(C1=CC=C([N+]([O-])=O)O1)(C2=CC=C(C)C=C2)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200