ICC/IF analysis of PFA fixed HeLa cells using GTX89581 Nucleophosmin antibody, C-term. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton Dilution : 10microg/ml
ICC/IF analysis of PFA fixed HeLa cells using GTX89581 Nucleophosmin antibody, C-term. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton Dilution : 10microg/ml
Nucleophosmin antibody, C-term
GTX89581
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetNPM1
Overview
- SupplierGeneTex
- Product NameNucleophosmin antibody, C-term
- Delivery Days Customer9
- Antibody SpecificityThis antibody is expected to recognise both report isoforms (NP_002511.1; NP_954654.1).
- Application Supplier NoteWB: 0.03-0.1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID4869
- Target nameNPM1
- Target descriptionnucleophosmin 1
- Target synonymsB23; NPM; nucleolar protein NO38; nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin/nucleoplasmin family, member 1; testicular tissue protein Li 128
- HostGoat
- IsotypeIgG
- Protein IDP06748
- Protein NameNucleophosmin
- Scientific DescriptionThe protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203