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ProductsBack/NUMB (C) Antibody, Rabbit Polyclonal

NUMB (C) Antibody, Rabbit Polyclonal

ORB67106
Biorbyt
TargetNUMB
Product group Antibodies
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Overview

  • Supplier
    Biorbyt
  • Product Name
    NUMB antibody
  • Delivery Days Customer
    16
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Gene ID8650
  • Target name
    NUMB
  • Target description
    NUMB endocytic adaptor protein
  • Target synonyms
    c14_5527; C14orf41; h-Numb; numb homolog; protein numb homolog; S171
  • Protein IDP49757
  • Protein Name
    Protein numb homolog
  • Scientific Description
    Rabbit polyclonal to NUMB.NUMB is a membrane-bound protein that has been shown to associate with EPS15, LNX1, andNOTCH1. NUMB is required throughout embryonic neurogenesis to maintain neural progenitor cells,also called radial glial cells GCs), by allowing their daughter cells to choose progenitor overneuronal cell fate. NUMB is not required for the proliferation of neural progenitor cells before the onsetof neurogenesis. NUMB is also involved postnatally in the subventricular zone (SVZ) neurogenesis byregulating SVZ neuroblasts survival and ependymal wall integrity. In addition, NUMB may mediatelocal repair of brain ventricular wall damage.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203