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ProductsBack/NUMB antibody

NUMB antibody

Research Use Only
ORB67106
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetNUMB
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Overview

  • Supplier
    Biorbyt
  • Product Name
    NUMB antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID8650
  • Target name
    NUMB
  • Target description
    NUMB endocytic adaptor protein
  • Target synonyms
    c14_5527; C14orf41; h-Numb; numb homolog; protein numb homolog; S171
  • Host
    Rabbit
  • Protein IDP49757
  • Protein Name
    Protein numb homolog
  • Scientific Description
    Rabbit polyclonal to NUMB.NUMB is a membrane-bound protein that has been shown to associate with EPS15, LNX1, andNOTCH1. NUMB is required throughout embryonic neurogenesis to maintain neural progenitor cells,also called radial glial cells GCs), by allowing their daughter cells to choose progenitor overneuronal cell fate. NUMB is not required for the proliferation of neural progenitor cells before the onsetof neurogenesis. NUMB is also involved postnatally in the subventricular zone (SVZ) neurogenesis byregulating SVZ neuroblasts survival and ependymal wall integrity. In addition, NUMB may mediatelocal repair of brain ventricular wall damage.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203