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O-GlcNAc transferase antibody

GTX109939
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetOGT
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Overview

  • Supplier
    GeneTex
  • Product Name
    O-GlcNAc transferase antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.51 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8473
  • Target name
    OGT
  • Target description
    O-linked N-acetylglucosamine (GlcNAc) transferase
  • Target synonyms
    HINCUT-1, HRNT1, MRX106, O-GLCNAC, OGT1, XLID106, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, O-GlcNAc transferase p110 subunit, O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase), O-linked N-acetylglucosamine transferase 110 kDa subunit, UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase, uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO15294
  • Protein Name
    UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
  • Scientific Description
    O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Huang YJ, Hsu SH. TRAIL-functionalized gold nanoparticles selectively trigger apoptosis in polarized macrophages. Nanotheranostics. 2017,1(3):326-337. doi: 10.7150/ntno.20233
    Read this paper
  • Nagai-Okatani C, Minamino N. Aberrant Glycosylation in the Left Ventricle and Plasma of Rats with Cardiac Hypertrophy and Heart Failure. PLoS One. 2016,11(6):e0150210. doi: 10.1371/journal.pone.0150210
    Read this paper
  • Sammartino G, Dohan Ehrenfest DM, Shibli JA, et al. Tissue Engineering and Dental Implantology: Biomaterials, New Technologies, and Stem Cells. Biomed Res Int. 2016,2016:5713168. doi: 10.1155/2016/5713168
    Read this paper
  • Chen YJ, Yao CC, Huang CH, et al. Hexosamine-Induced TGF-β Signaling and Osteogenic Differentiation of Dental Pulp Stem Cells Are Dependent on N-Acetylglucosaminyltransferase V. Biomed Res Int. 2015,2015:924397. doi: 10.1155/2015/924397
    Read this paper
  • Komura K, Ise H, Akaike T. Dynamic behaviors of vimentin induced by interaction with GlcNAc molecules. Glycobiology. 2012,22(12):1741-59. doi: 10.1093/glycob/cws118
    Read this paper
  • Ise H, Goto M, Komura K, et al. Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin. Glycobiology. 2012,22(6):788-805. doi: 10.1093/glycob/cws052
    Read this paper