o-Phenanthroline
S6830
Estimated Purity...
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product Nameo-Phenanthroline
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific Descriptiono-Phenanthroline (1,10-Phenanthroline, phen), a hypoxia-mimicking agent, is a non-specific matrix metalloproteinase (MMP) inhibitor with IC50 of 110.5microM for Collagenase. O-phenanthroline reduces the expression of MMP3 and MMP13 mRNA levels during chondrogenic differentiation of human chondrocytes (hChs), as well as after TNFalpha/IL-1beta exposure in an explant model. o-Phenanthroline is also a metal chelator which prevents the induction of chromosomal aberrations in streptozotocin-treated cells and forms a red chelate with Fe2+ that absorbs maximally at 510 nm.
- UNSPSC51202000
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