OAS1 Polyclonal Antibody

Reddot Biotech

OAS1 Polyclonal Antibody

5

ImmunoFluorescence, Western Blot

Research Use Only

1 mg/ml

Unconjugated

OAS1

2'-5'-oligoadenylate synthetase 1

(2-5')oligo(A) synthase 1; 2',5'-oligo A synthetase 1; 2-5A synthase 1; 2-5A synthetase 1; 2'-5'-oligoadenylate synthase 1; 2'-5'-oligoadenylate synthetase 1, 40/46kDa; 2'-5'-oligoisoadenylate synthetase 1; E16 (2'-5') oligo A synthetase; E18/E16; IFI-4; OIAS; OIASI

Rabbit

IgG

This gene is induced by interferons and encodes a protein that synthesizes 2,5-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.

Human, Mouse

-20°C

12352203