OAS2 antibody, N-term

GeneTex

OAS2 antibody, N-term

9

WB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

OAS2

2'-5'-oligoadenylate synthetase 2

(2'-5')oligo(A) synthetase 2; 2-5A synthase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; p69 OAS / p71 OAS

Rabbit

IgG

2'-5'-oligoadenylate synthase 2

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2-specific nucleotidyl transfer reactions to synthesize 2,5-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203