Obatoclax [803712-67-6]

MedChem Express

Obatoclax [803712-67-6]

10

803712-67-6

Research Use Only

99.0

C20H19N3O

317.38

Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a Ki of 220 nM for BCL-2[1][2]. Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity[3][4].

COC1=CC(C(N2)=CC3=C2C=CC=C3)=N/C1=C\C4=C(C)C=C(C)N4

-20°C,2°C to 8°C

12352200