Obatoclax [803712-67-6]

TargetMol Chemicals

Obatoclax [803712-67-6]

72

803712-67-6

Research Use Only

Obatoclax

99.44%

C20H19N3O

317.38

Obatoclax (GX15-070), a pan-BCL-2 family proteins inhibitor and BH3 mimetic, exhibits a binding affinity (K_i) of 220 nM for BCL-2. It promotes autophagy-dependent cell death and cyclin D1 degradation via the proteasome. Additionally, Obatoclax demonstrates anti-cancer properties and broad-spectrum antiparasitic activity.

3 years

C(=C1N=C(C=C1OC)C2=CC=3C(N2)=CC=CC3)C4=C(C)C=C(C)N4

-20°C

12352200