Obatoclax (Mesylate)

MedChem Express

Obatoclax (Mesylate) [803712-79-0]

10

803712-79-0

Research Use Only

99.85

C21H23N3O4S

413.49

Obatoclax Mesylate (GX15-070 Mesylate), a BH3 mimetic, is a pan- BCL-2 family proteins inhibitor with a K i of 220 nM for BCL-2 [1] [2] . Obatoclax Mesylate induces autophagy -dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax Mesylate has anti-cancer and broad-spectrum antiparasitic activity [3] [4] .

COC1=CC(C2=CC3=C(C=CC=C3)N2)=N/C1=C\C4=C(C=C(N4)C)C.CS(=O)(O)=O

2°C to 8°C

12352200