Olaparib (AZD2281)

Selleck Chemicals

Olaparib (AZD2281) [763113-22-0]

9

Research Use Only

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Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations.

-80°C

51202000