Oleocanthal [289030-99-5]

MedChem Express

Oleocanthal [289030-99-5]

14

289030-99-5

Research Use Only

99.0

C17H20O5

304.34

Oleocanthal is an orally active phenolic seciridoid compound. Oleocanthal can be extracted from olive oil. Oleocanthal inhibits COX-1 and COX-2, reduces ROS and NO, and upregulates Nrf-2 and HO-1. Oleocanthal reduces Abeta deposition. Oleocanthal exhibits anti-Leishmania activity against promastigotes and amastigotes of L. major, with IC50 values of 18.7 and 87 microg/mL, respectively. Oleocanthal exhibits anticancer activity against colon, breast, liver, and melanoma cancers. Oleocanthal also exhibits anti-inflammatory and neuroprotective properties. Oleocanthal can be used in Alzheimers disease research[1][2][3][4][5][6].

C/C=C([C@H](CC(OCCC1=CC=C(C=C1)O)=O)CC=O)/C=O

-20°C

12131703