ELISA analysis of human OPG recombinant protein (0.2 - 0.4 ng/well) using GTX18068 OPG antibody (Biotin). Working concentration : 0.25- 1.0 ug/ml
OPG antibody (Biotin)
GTX18068
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetTNFRSF11B
Overview
- SupplierGeneTex
- Product NameOPG antibody (Biotin)
- Delivery Days Customer9
- Application Supplier NoteWB: 0.1 - 0.2 microg/mL. ELISA: 0.15 - 0.30 microg/mL. Sandwich ELISA: 0.25 - 1.0 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- FormulationLiquid
- Gene ID4982
- Target nameTNFRSF11B
- Target descriptionTNF receptor superfamily member 11b
- Target synonymsOCIF; OPG; osteoclastogenesis inhibitory factor; osteoprotegerin; PDB5; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b
- HostRabbit
- IsotypeIgG
- Protein IDO00300
- Protein NameTumor necrosis factor receptor superfamily member 11B
- Scientific DescriptionOsteoprotegerin (OPG) belongs to the TNF receptor (TNFR) family. Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203