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WB analysis of various sample lysates using GTX55734 OPG antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX55734 OPG antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX55734 OPG antibody. Dilution : 1:1000 Loading : 25microg per lane

OPG antibody

GTX55734
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTNFRSF11B
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Overview

  • Supplier
    GeneTex
  • Product Name
    OPG antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. ICC/IF: 1:10 - 1:100. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4982
  • Target name
    TNFRSF11B
  • Target description
    TNF receptor superfamily member 11b
  • Target synonyms
    OCIF; OPG; osteoclastogenesis inhibitory factor; osteoprotegerin; PDB5; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00300
  • Protein Name
    Tumor necrosis factor receptor superfamily member 11B
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Biomodulation of Induced Tooth Movement by Three Methods, Corticopuncture, Photobiomodulation, and Their Combination: An Animal Study.
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  • ZEB1 regulates bone metabolism in osteoporotic rats through inducing POLDIP2 transcription.
    Read more
  • Probiotic Propionibacterium freudenreichii MJ2 Enhances Osteoblast Differentiation and Mineralization by Increasing the OPG/RANKL Ratio. Yeom J et al., 2021 Mar 24, Microorganisms
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  • RANKL expression of primary osteoblasts is enhanced by an IL-17-mediated JAK2/STAT3 pathway through autophagy suppression. Wang Z et al., 2021 Jul, Connect Tissue Res
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