
WB analysis of various sample lysates using GTX55734 OPG antibody. Dilution : 1:1000 Loading : 25microg per lane
OPG antibody
GTX55734
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTNFRSF11B
Overview
- SupplierGeneTex
- Product NameOPG antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:10 - 1:100. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4982
- Target nameTNFRSF11B
- Target descriptionTNF receptor superfamily member 11b
- Target synonymsOCIF; OPG; osteoclastogenesis inhibitory factor; osteoprotegerin; PDB5; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b
- HostRabbit
- IsotypeIgG
- Protein IDO00300
- Protein NameTumor necrosis factor receptor superfamily member 11B
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Biomodulation of Induced Tooth Movement by Three Methods, Corticopuncture, Photobiomodulation, and Their Combination: An Animal Study.Read more
- ZEB1 regulates bone metabolism in osteoporotic rats through inducing POLDIP2 transcription.Read more
- Probiotic Propionibacterium freudenreichii MJ2 Enhances Osteoblast Differentiation and Mineralization by Increasing the OPG/RANKL Ratio. Yeom J et al., 2021 Mar 24, MicroorganismsRead more
- RANKL expression of primary osteoblasts is enhanced by an IL-17-mediated JAK2/STAT3 pathway through autophagy suppression. Wang Z et al., 2021 Jul, Connect Tissue ResRead more