Ophiopogonin D

MedChem Express

Ophiopogonin D [65604-80-0]

10

65604-80-0

Research Use Only

99.85

C44H70O16

855.02

Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus , is a rare naturally occurring C 29 steroidal glycoside. Ophiopogonin D shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC 50 s of 3.09 microM and 3.63 microM, respectively [1] . Ophiopogonin D activates SIRT1 in a dose-dependent manner [2] .

C[C@@]12[C@]3([H])[C@](O[C@]4(CC[C@@H](C)CO4)[C@H]3C)([H])C[C@@]1([H])[C@@]5([H])[C@]([C@@]6(C(C[C@@H](O[C@@]7([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O7)O[C@@]8([H])[C@@H]([C@H]([C@H](O)CO8)O)O)O[C@@]9([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O9)O)O)CC6)=CC5)C)([H])CC2

2°C to 8°C

12352200