Ophiopogonin D'

AbMole BioScience

Ophiopogonin D'

9

65604-80-0

Chemical

Research Use Only

C44H70O16

855.02

Ophiopogonin D', isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D' has cytotoxic activity against two human tumor cell lines mG-63 and SNU387. Ophiopogonin D' can induce necrotic apoptosis of prostate cancer LNCaP cells by activating RIPK1. IC50 were 3.09 uM and 3.63 uM, respectively. SIRT1 is activated in a dose-dependent manner by Ophiopogonin D'.

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