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ProductsBack/OTC antibody

OTC antibody

GTX105140
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetOTC
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Overview

  • Supplier
    GeneTex
  • Product Name
    OTC antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:30000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.65 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5009
  • Target name
    OTC
  • Target description
    ornithine transcarbamylase
  • Target synonyms
    OCTD; ornithine carbamoyltransferase, mitochondrial; ornithine transcarbamylase, mitochondrial; OTCase; OTCD
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00480
  • Protein Name
    Ornithine carbamoyltransferase, mitochondrial
  • Scientific Description
    This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response.
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  • Humanized liver mouse model with transplanted human hepatocytes from patients with ornithine transcarbamylase deficiency. Sugahara G et al., 2021 May, J Inherit Metab Dis
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  • Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice. Wang X et al., 2018 Sep 1, J Nutr
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  • Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells. Agrawal V et al., 2012 Jan, Anticancer Drugs
    Read more