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OTC antibody

GTX105140
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetOTC
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Overview

  • Supplier
    GeneTex
  • Product Name
    OTC antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:30000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.65 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5009
  • Target name
    OTC
  • Target description
    ornithine transcarbamylase
  • Target synonyms
    OCTD, OTC1, OTCD, OTCase, ornithine transcarbamylase, mitochondrial, ornithine carbamoyltransferase, mitochondrial
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00480
  • Protein Name
    Ornithine transcarbamylase, mitochondrial
  • Scientific Description
    This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chida T, Ishida Y, Morioka S, et al. Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response. JCI Insight. 2023,8(9). doi: 10.1172/jci.insight.162404
    Read this paper
  • Sugahara G, Yamasaki C, Yanagi A, et al. Humanized liver mouse model with transplanted human hepatocytes from patients with ornithine transcarbamylase deficiency. J Inherit Metab Dis. 2021,44(3):618-628. doi: 10.1002/jimd.12347
    Read this paper
  • Wang X, Yuan Y, Didelija IC, et al. Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice. J Nutr. 2018,148(9):1415-1420. doi: 10.1093/jn/nxy126
    Read this paper
  • Agrawal V, Woo JH, Mauldin JP, et al. Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells. Anticancer Drugs. 2012,23(1):51-64. doi: 10.1097/CAD.0b013e32834ae42b
    Read this paper

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