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Boiled and unboiled HepG2 membrane extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with P Glycoprotein antibody (GTX108354) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)
Boiled and unboiled HepG2 membrane extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with P Glycoprotein antibody (GTX108354) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)
Boiled and unboiled HepG2 membrane extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with P Glycoprotein antibody (GTX108354) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)

P Glycoprotein antibody

GTX108354
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetABCB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    P Glycoprotein antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.58 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5243
  • Target name
    ABCB1
  • Target description
    ATP binding cassette subfamily B member 1
  • Target synonyms
    ABC20, CD243, CLCS, ENPAT, GP170, MDR1, P-GP, PGY1, p-170, ATP-dependent translocase ABCB1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, P-glycoprotein 1, colchicin sensitivity, doxorubicin resistance, multidrug resistance protein 1, phospholipid transporter ABCB1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08183
  • Protein Name
    ATP-dependent translocase ABCB1
  • Scientific Description
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161