ProductsBack/p130Cas antibody [N2C2], Internal

p130Cas antibody [N2C2], Internal

Name: p130Cas antibody [N2C2], Internal
SKU: GTX100605_G10
Availability: BackOrder

GTX100605

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetBCAR1

Overview

Supplier
GeneTex
Product Name
p130Cas antibody [N2C2], Internal
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.38 mg/ml
Conjugate
Unconjugated
Gene ID9564
Target name
BCAR1
Target description
BCAR1 scaffold protein, Cas family member
Target synonyms
CAS, CAS1, CASS1, CRKAS, P130Cas, breast cancer anti-estrogen resistance protein 1, BCAR1, Cas family scaffold protein, BCAR1, Cas family scaffolding protein, Cas scaffolding protein family member 1, Crk-associated substrate p130Cas
Host
Rabbit
Isotype
IgG
Protein IDP56945
Protein Name
Breast cancer anti-estrogen resistance protein 1
Scientific Description
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Kumar A, Tanaka K, Schwartz MA. Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation. bioRxiv. 2024,:pii: 2023.11.22.568289. doi: 10.1101/2023.11.22.568289.
Read this paper
Zhang X, Moore SW, Iskratsch T, et al. N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading. J Cell Sci. 2014,127(Pt 7):1394-405. doi: 10.1242/jcs.134692
Read this paper