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P2X7 antibody

GTX104288
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetP2RX7
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Overview

  • Supplier
    GeneTex
  • Product Name
    P2X7 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5027
  • Target name
    P2RX7
  • Target description
    purinergic receptor P2X 7
  • Target synonyms
    ATP receptor; P2X purinoceptor 7; P2X7; P2X7 receptor; P2Z receptor; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X7 variant A; purnergic receptor P2X 7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ99572
  • Protein Name
    P2X purinoceptor 7
  • Scientific Description
    The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Dorsal root ganglia P2X4 and P2X7 receptors contribute to diabetes-induced hyperalgesia and the downregulation of electroacupuncture on P2X4 and P2X7.
    Read more
  • Role of P2X7R in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps. Wang Y et al., 2021 Jul, Mol Med Rep
    Read more

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