IHC-P analysis of human placenta tissue using GTX01862 p57 Kip2 antibody [25B2]. Note nuclear staining for cytotrophoblast and stromal cells of the villi.
IHC-P analysis of human placenta tissue using GTX01862 p57 Kip2 antibody [25B2]. Note nuclear staining for cytotrophoblast and stromal cells of the villi.
p57 Kip2 antibody [25B2]
GTX01862
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCDKN1C
Overview
- SupplierGeneTex
- Product Namep57 Kip2 antibody [25B2]
- Delivery Days Customer9
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID25B2
- ConjugateUnconjugated
- Gene ID1028
- Target nameCDKN1C
- Target descriptioncyclin dependent kinase inhibitor 1C
- Target synonymsBWCR; BWS; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; KIP2; p57; p57Kip2; WBS
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Effect of butyrate, a bacterial by-product, on the viability and ICAM-1 expression/production of human vascular endothelial cells: Role in infectious pulpal/periapical diseases. Chang MC et al., 2022 Jan, Int Endod JRead more