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WB analysis of 293 cell lysate using GTX31859 p57 Kip2 antibody. Working concentration : (A) 1 and (B) 2 microg/ml
WB analysis of 293 cell lysate using GTX31859 p57 Kip2 antibody. Working concentration : (A) 1 and (B) 2 microg/ml
WB analysis of 293 cell lysate using GTX31859 p57 Kip2 antibody. Working concentration : (A) 1 and (B) 2 microg/ml

p57 Kip2 antibody

GTX31859
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetCDKN1C
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Overview

  • Supplier
    GeneTex
  • Product Name
    p57 Kip2 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    At least three isoforms are known to exist; this antibody will detect all three isoforms. This antibody is predicted to not cross react with other CIP/KIP proteins.
  • Application Supplier Note
    WB: 1 - 2 microg/mL. ICC/IF: 20 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1028
  • Target name
    CDKN1C
  • Target description
    cyclin dependent kinase inhibitor 1C
  • Target synonyms
    BWCR; BWS; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; KIP2; p57; p57Kip2; WBS
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP49918
  • Protein Name
    Cyclin-dependent kinase inhibitor 1C
  • Scientific Description
    This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Effect of Butyrate on Collagen Expression, Cell Viability, Cell Cycle Progression and Related Proteins Expression of MG-63 Osteoblastic Cells. Chang MC et al., 2016, PLoS One
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