Pacritinib

MedChem Express

Pacritinib [937272-79-2]

9

937272-79-2

Research Use Only

99.93

C28H32N4O3

472.58

Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC 50 =23 nM) and JAK2 V617F mutant (IC 50 =19 nM). Pacritinib also inhibits FLT3 (IC 50 =22 nM) and its mutant FLT3 D835Y (IC 50 =6 nM).

C1(COC/C=C/COCC2=C(OCCN3CCCC3)C=CC4=C2)=CC=CC(C5=N/C(NC=C5)=N\4)=C1

-20°C,2°C to 8°C

12352200