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Pacritinib

M2912
AbMole BioScience
CAS Number937272-79-2
Product group Chemicals
Molecular Weight472.58
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Pacritinib
  • Delivery Days Customer
    9
  • CAS Number
    937272-79-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C28H32N4O3
  • Molecular Weight
    472.58
  • Scientific Description
    Pacritinib (SB1518) is an effective mutant inhibitor of wild-type JAK2 and JAK2V617F with IC50 of 23 nM and 19 nM, respectively. Pacritinib also inhibited FLT3 and its mutant FLT3D835Y with IC50 of 22 nM and 6 nM, respectively.
  • SMILES
    C1CCN(C1)CCOC2=CC=C3NC4=NC=CC(=N4)C5=CC(=CC=C5)COC\C=C\COCC2=C3
  • UNSPSC
    12352200

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