PAN2 Antibody

Cusabio

PAN2 Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

PAN2

poly(A) specific ribonuclease subunit PAN2

USP52, PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAB-dependent poly(A)-specific ribonuclease subunit 2, PAB-dependent poly(A)-specific ribonuclease subunit PAN2, PAB1P-dependent poly(A)-nuclease, PAB1P-dependent poly(A)-specific ribonuclease, PABP-dependent poly(A) nuclease 2, PAN deadenylation complex catalytic subunit 2, PAN deadenylation complex subunit 2, PAN2 poly(A) specific ribonuclease subunit homolog, inactive ubiquitin carboxyl-terminal hydrolase 52, poly(A)-nuclease deadenylation complex subunit 2, ubiquitin specific peptidase 52, ubiquitin specific protease 52

Rabbit

IgG

PAN2-PAN3 deadenylation complex catalytic subunit PAN2

Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA when the poly(A) stretch is bound by poly(A)-binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3-5 exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5-3 exonucleolytic degradation by XRN1.

Human

-20°C or -80°C

41116161