Western blot analysis of extracts of various cell lines using PARN Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using PARN Polyclonal Antibody at 1:1000 dilution.
PARN Polyclonal Antibody
E-AB-65461
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePARN Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a 3-exoribonuclease, with similarity to the RNase D family of 3-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203