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PB28 dihydrochloride [172907-03-8]

PB28 dihydrochloride [172907-03-8]

T23122
TargetMol Chemicals
CAS Number172907-03-8
Product group Chemicals
Molecular Weight443.49
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PB28 dihydrochloride [172907-03-8]
  • Delivery Days Customer
    14
  • CAS Number
    172907-03-8
  • Certification
    Research Use Only
  • Chemical Name
    PB28 dihydrochloride
  • Molecular Formula
    C24H40Cl2N2O
  • Molecular Weight
    443.49
  • Scientific Description
    PB28 dihydrochloride is a selective and potent sigma 2 (sigma2) receptor agonist and sigma1 receptor antagonist with anti-SARS-CoV-2 activity and anti-tumor activity, which inhibits cell proliferation and invasion and suppresses SKF by modulating the PI3K-AKT-mTOR signaling pathway in renal cancer. It inhibits cell proliferation and invasion by regulating the PI3K-AKT-mTOR signaling pathway in renal cancer, inhibits calcium release from the endoplasmic reticulum of SK-N-SH neuroblastoma cells, and induces non-caspase-dependent apoptosis.
  • Shelf life instruction
    3 years
  • SMILES
    COC1=CC=CC2=C1CCCC2CCCN3CCN(C4CCCCC4)CC3.Cl.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200