ProductsBack/PBR antibody, C-term

WB analysis of human breast cancer lysate using GTX89258 PBR antibody, C-term. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer

PBR antibody, C-term

GTX89258

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman

TargetTSPO

Overview

Supplier
GeneTex
Product Name
PBR antibody, C-term
Delivery Days Customer
7
Antibody Specificity
This antibody is expected to recognise one isoform (NP_000705.2) only.
Application Supplier Note
WB: 0.1-0.3microg/ml. IHC-P: 5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.50 mg/ml
Conjugate
Unconjugated
Gene ID706
Target name
TSPO
Target description
translocator protein
Target synonyms
benzodiazepine peripheral binding site; BPBS; BZRP; DBI; IBP; MBR; mDRC; mitochondrial benzodiazepine receptor; PBR; PBS; peripheral-type benzodiazepine receptor; pk18; PKBS; PTBR; translocator protein
Host
Goat
Isotype
IgG
Scientific Description
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

[11C]-(R)PK11195 tracer kinetics in the brain of glioma patients and a comparison of two referencing approaches. Su Z et al., 2013 Sep, Eur J Nucl Med Mol Imaging
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