Western Blot Positive WB detected in: Rat kidney tissue All lanes: PBX1 antibody at 4.7ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 47, 39 kDa Observed band size: 47 kDa

PBX1 Antibody

Name: PBX1 Antibody
SKU: CSB-PA017505LA01HU_C90
Availability: BackOrder

CSB-PA017505LA01HU

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetPBX1

Overview

Supplier
Cusabio
Product Name
PBX1 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID5087
Target name
PBX1
Target description
PBX homeobox 1
Target synonyms
CAKUHED; homeobox protein PBX1; homeobox protein PRL; pre-B-cell leukemia homeobox 1; pre-B-cell leukemia transcription factor 1
Host
Rabbit
Isotype
IgG
Protein IDP40424
Protein Name
Pre-B-cell leukemia transcription factor 1
Scientific Description
Binds the sequence 5-ATCAATCAA-3. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression (By similarity).
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

PBX1 Antibody

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Overview

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