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Immunofluorescence analysis of U2OS cells using PC Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using PC Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using PC Polyclonal Antibody

PC Polyclonal Antibody

E-AB-61871
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    PC Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5 UTRs, but encoding the same protein, have been found for this gene.
  • UNSPSC
    12352203