Bio-Connect
PD-L2 / PDCD1LG2 / CD273(PDL2/2676), CF405S conjugate, 0.1mg/mL [26628-22-8]

PD-L2 / PDCD1LG2 / CD273(PDL2/2676), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC042676
Biotium
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetPDCD1LG2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biotium
  • Product Name
    PD-L2 / PDCD1LG2 / CD273(PDL2/2676), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PDL2/2676
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID80380
  • Target name
    PDCD1LG2
  • Target description
    programmed cell death 1 ligand 2
  • Target synonyms
    B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; butyrophilin B7-DC; CD273; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; PDL2; PD-L2; programmed cell death 1 ligand 2; programmed death ligand 2
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203