PD98059
HY-12028
Overview
- SupplierMedChem Express
- Product NamePD98059 [167869-21-8]
- Delivery Days Customer5
- CAS Number167869-21-8
- CertificationResearch Use Only
- Estimated Purity99.96
- Molecular FormulaC16H13NO3
- Molecular Weight267.28
- Scientific DescriptionPD98059 is a potent and selective MEK inhibitor with an IC 50 of 5 microM. PD98059 binds to the inactive form of MEK , thereby preventing the activation of MEK1 ( IC 50 of 2-7 microM) and MEK2 ( IC 50 of 50 microM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) , and suppresses TCDD binding ( IC 50 of 4 microM) and AHR transformation ( IC 50 of 1 microM). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy [1] [2] [3] .
- SMILESO=C1C=C(OC2=CC=CC=C21)C3=CC=CC(OC)=C3N
- Storage Instruction2°C to 8°C
- UNSPSC12352200
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Estimated Purity98.56%
Molecular Weight267.28
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