PDE4B antibody

GeneTex

PDE4B antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.72 mg/ml

Unconjugated

PDE4B

phosphodiesterase 4B

cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DPDE4; dunce-like phosphodiesterase E4; PDEIVB; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)

Rabbit

IgG

cAMP-specific 3',5'-cyclic phosphodiesterase 4B

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203