PDE4B antibody

GeneTex

PDE4B antibody

9

This antibody detects all PDE4B proteins, including PDE4B1, PDE4B2, PDE4B3, and a 66 kDa PDE4B variant. It does not cross-react with other PDE family members such as PDE4A, PDE4C. And it may have minor crossreactivity to PDE4D.

WB: 1:500-1:1000. ICC/IF: 1:250. IHC-P: 1:250. IHC-Fr: 1:250. IP: 1:350. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.68 mg/ml

Unconjugated

PDE4B

phosphodiesterase 4B

cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DPDE4; dunce-like phosphodiesterase E4; PDEIVB; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)

Rabbit

IgG

cAMP-specific 3',5'-cyclic phosphodiesterase 4B

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203