Whole cell extract (30 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with PDE6D antibody [N1C3] (GTX109240) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
![PDE6D antibody [N1C3] detects PDE6D protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PDE6D stained by PDE6D antibody [N1C3] (GTX109240) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000. Scale bar= 10μm.](https://www.genetex.com/upload/website/prouct_img/normal/GTX109240/GTX109240_44349_20220408_ICC_IF_w_23060120_491.webp "PDE6D antibody [N1C3] detects PDE6D protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PDE6D stained by PDE6D antibody [N1C3] (GTX109240) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000. Scale bar= 10μm.")
![Mouse tissue extract (50 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with PDE6D antibody [N1C3] (GTX109240) diluted at 1:15000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX109240/GTX109240_40023_20170105_WB_M_eye_w_23060120_663.webp "Mouse tissue extract (50 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with PDE6D antibody [N1C3] (GTX109240) diluted at 1:15000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.")
Whole cell extract (30 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with PDE6D antibody [N1C3] (GTX109240) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
PDE6D antibody [N1C3]
GTX109240
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPDE6D
Overview
- SupplierGeneTex
- Product NamePDE6D antibody [N1C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.17 mg/ml
- ConjugateUnconjugated
- Gene ID5147
- Target namePDE6D
- Target descriptionphosphodiesterase 6D
- Target synonymsJBTS22, PDED, retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, GMP-PDE delta, phosphodiesterase 6D, cGMP-specific, rod, delta, protein p17
- HostRabbit
- IsotypeIgG
- Protein IDO43924
- Protein NameRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chen L, Zhang J, Wang X, et al. Discovery of novel KRAS‒PDEδ inhibitors with potent activity in patient-derived human pancreatic tumor xenograft models. Acta Pharm Sin B. 2022,12(1):274-290. doi: 10.1016/j.apsb.2021.07.009Read this paper
- Dumbacher M, Van Dooren T, Princen K, et al. Modifying Rap1-signalling by targeting Pde6δ is neuroprotective in models of Alzheimer's disease. Mol Neurodegener. 2018,13(1):50. doi: 10.1186/s13024-018-0283-3Read this paper
Datasheet
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