
WB analysis of non-reduced and heated sample lysates using GTX14619 PDE8A antibody. Lane 1 : SDS-solubilized PDE8 cytosol fraction Lane 2 : SDS-solubilized treated-PDE8 cytosol fraction Lane 3 : SDS-solubilized PDE8 cell membrane fraction
PDE8A antibody
GTX14619
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Human, Monkey, Mouse, Rat
TargetPDE8A
Overview
- SupplierGeneTex
- Product NamePDE8A antibody - Orthogonal Validated
- Delivery Days Customer9
- Antibody SpecificityThis antibody will label only PDE8A variants. This antibody will not cross react with other PDE family members.
- Application Supplier NoteWB: 1:500-1:2000. ICC/IF: 1:250. IP: 1:250. ELISA: 1:10000. IHC: 1:250. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID5151
- Target namePDE8A
- Target descriptionphosphodiesterase 8A
- Target synonymscAMP-specific cyclic nucleotide phosphodiesterase 8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A; HsT19550
- HostRabbit
- IsotypeIgG
- Protein IDO60658
- Protein NameHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
- Scientific DescriptionThe protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
- ReactivityBovine, Human, Monkey, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203