PDGF Receptor alpha antibody
GTX133619
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse
TargetPDGFRA
Overview
- SupplierGeneTex
- Product NamePDGF Receptor alpha antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.59 mg/ml
- ConjugateUnconjugated
- Gene ID5156
- Target namePDGFRA
- Target descriptionplatelet derived growth factor receptor alpha
- Target synonymsCD140A, PDGFR-2, PDGFR2, platelet-derived growth factor receptor alpha, CD140 antigen-like family member A, CD140a antigen, PDGF-R-alpha, alpha-type platelet-derived growth factor receptor, platelet-derived growth factor receptor 2, platelet-derived growth factor receptor, alpha polypeptide
- HostRabbit
- IsotypeIgG
- Protein IDP16234
- Protein NamePlatelet-derived growth factor receptor alpha
- Scientific DescriptionThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cullen CL, O'Rourke M, Beasley SJ, et al. Kif3a deletion prevents primary cilia assembly on oligodendrocyte progenitor cells, reduces oligodendrogenesis and impairs fine motor function. Glia. 2021,69(5):1184-1203. doi: 10.1002/glia.23957Read this paper
- Pitman KA, Ricci R, Gasperini R, et al. The voltage-gated calcium channel CaV1.2 promotes adult oligodendrocyte progenitor cell survival in the mouse corpus callosum but not motor cortex. Glia. 2020,68(2):376-392. doi: 10.1002/glia.23723Read this paper
![IHC-P analysis of formalin fixed human placenta tissue using GTX52457 PDGF Receptor alpha antibody [8A89].](https://www.genetex.com/upload/website/prouct_img/normal/GTX52457/GTX52457_20191119_IHC-P_w_23060900_329.webp)
![FACS analysis of CD140a-transfected 3T3 cells using GTX80300 PDGF Receptor alpha antibody [16A1] (APC).](https://www.genetex.com/upload/website/prouct_img/normal/GTX80300/GTX80300_20191028_FACS_1_w_23061322_239.webp)
