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PDX1 Polyclonal Antibody

RD80262A
Reddot Biotech
ApplicationsWestern Blot
Product group Antibodies
TargetPDX1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PDX1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3651
  • Target name
    PDX1
  • Target description
    pancreatic and duodenal homeobox 1
  • Target synonyms
    glucose-sensitive factor; GSF; IDX-1; insulin promoter factor 1, homeodomain transcription factor; insulin upstream factor 1; IPF1; IPF-1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; pancreas/duodenum homeobox protein 1; pancreatic-duodenal homeobox factor 1; PDX-1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; STF-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

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