PDZK1 antibody [AT1A2]

GeneTex

PDZK1 antibody [AT1A2]

9

The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.

Western Blot, ELISA

Research Use Only

Monoclonal

AT1A2

1 mg/ml

Unconjugated

PDZK1

PDZ domain containing 1

CAP70; CFTR-associated protein of 70 kDa; CLAMP; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; na/Pi cotransporter C-terminal-associated protein 1; naPi-Cap1; NHERF3; NHERF-3; PDZ-containing kidney protein 1; PDZD1; sodium-hydrogen exchanger regulatory factor 3

Mouse

IgG2b

Na(+)/H(+) exchange regulatory cofactor NHE-RF3

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

-20°C or -80°C,2°C to 8°C

12352203