PE/Cyanine5.5 Anti-Mouse CD40 Antibody

Reddot Biotech

PE/Cyanine5.5 Anti-Mouse CD40 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

FGK4.5/FGK45

0.2 mg/ml

Double Conjugated

Cd40

CD40 antigen

AI326936; B-cell surface antigen CD40; Bp5; Bp50; CD40L receptor; GP39; HIGM1; IGM; IMD3; p5; p50; T-BAM; T-cell differentiation antigen; Tnfr; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5

Rat

IgG2a

CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Mouse

2°C to 8°C

12352203