PE/Cyanine5.5 Anti-Mouse Ly6A/E(Sca-1) Antibody

Reddot Biotech

PE/Cyanine5.5 Anti-Mouse Ly6A/E(Sca-1) Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

D7

Double Conjugated

Ly6a

lymphocyte antigen 6 complex, locus A

Ly-6A; Ly-6A.2; Ly-6A/E; Ly-6E.; Ly-6E.1; lymphocyte antigen 6A-2/6E-1; Sc; Sca; Sca1; Sca-1; stem cell antigen 1; T; TAP; T-cell-activating protein

Rat

IgG2a

Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Mouse

2°C to 8°C

12352203