Bio-Connect

PerCP/Cyanine5.5 Anti-Human CD40 Antibody

RD20565F
Reddot Biotech
TargetCD40
Product group Antibodies
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PerCP/Cyanine5.5 Anti-Human CD40 Antibody
  • Delivery Days Customer
    5
  • Clone ID
    3A8
  • Gene ID958
  • Target name
    CD40
  • Target description
    CD40 molecule
  • Target synonyms
    B cell surface antigen CD40; B cell-associated molecule; Bp50; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDW40; p50; TNFRSF5; tumor necrosis factor receptor superfamily member 5
  • Scientific Description
    CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203