PerCP/Cyanine5.5 Anti-Human CD61 Antibody

Reddot Biotech

PerCP/Cyanine5.5 Anti-Human CD61 Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

VI-PL2

Double Conjugated

ITGB3

integrin subunit beta 3

antigen CD61; BDPLT16; BDPLT2; BDPLT24; CD61; GP3A; GPIIIa; GT; GT2; integrin beta 3; integrin beta chain, beta 3; integrin beta-3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet membrane glycoprotein IIIa

Mouse

IgG1

CD61, also known as integrin beta3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin Oe+/-V (CD51) to form Oe+/-V/beta3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

Human

2°C to 8°C

12352203