
WB analysis of MCF-7 cells using GTX47089 PPL antibody at 0.2-1microg/ml.
Periplakin antibody, Internal
GTX47089
Overview
- SupplierGeneTex
- Product NamePeriplakin antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID5493
- Target namePPL
- Target descriptionperiplakin
- Target synonyms190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; periplakin
- HostRabbit
- IsotypeIgG
- Protein IDO60437
- Protein NamePeriplakin
- Scientific DescriptionThe protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203