PF-3450074 [1352879-65-2]
HY-120072
CAS Number1352879-65-2
Product group Chemicals
Estimated Purity98.89
Molecular Weight425.52
Overview
- SupplierMedChem Express
- Product NamePF-3450074 [1352879-65-2]
- Delivery Days Customer9
- CAS Number1352879-65-2
- CertificationResearch Use Only
- Estimated Purity98.89
- Molecular FormulaC27H27N3O2
- Molecular Weight425.52
- Scientific DescriptionPF-3450074 (PF-74) is a specifical inhibitor of HIV-1 capsid protein (CA) and displays a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640 nM). PF-3450074 (PF-74) acts at an early stage of HIV-1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle[1][2]. CPSF6: nuclear host factors cleavage and polyadenylation specific factor 6; NUP153: nucleoporin 153.
- SMILESO=C(N[C@@H](CC1=CC=CC=C1)C(N(C)C2=CC=CC=C2)=O)CC3=C(C)NC4=C3C=CC=C4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number1352879-65-2
Estimated Purity99.92%
Molecular Weight425.52
- SizePrice
Product group Chemicals
PF-3450074ORB1307896
CAS Number1352879-65-2
Estimated Purity99.92%
Molecular Weight425.52
- SizePrice